1 · Stimulation Protocols
Long agonist, antagonist (the modern default), mild/mini-IVF, random-start, DuoStim. Which protocol matches which patient, and why one-size-fits-all is a red flag.
This is the conversation your doctor does not always have time for. Written for couples who have already done the basics — read the free guide, maybe done a cycle or two — and want to understand what is happening at a deeper level. The homework that makes your next consult ten times more useful. ₹149.
New to IVF? Start with the free IVF Basic Guide →
Built for the couple who is mid-cycle, considering a second opinion, or already had a cycle that did not go the way they hoped. Each chapter walks through the choices, the evidence, and the questions to ask.
Long agonist, antagonist (the modern default), mild/mini-IVF, random-start, DuoStim. Which protocol matches which patient, and why one-size-fits-all is a red flag.
hCG, GnRH agonist, dual trigger. Given 36 hours before retrieval — the injection that decides whether eggs finish maturing. Which one for which patient.
ICSI is used in 70%+ of cycles globally. Often it shouldn't be. When ICSI is genuinely needed, when it is being oversold, and the live-birth data.
Cleavage-stage vs blastocyst transfer, and the Gardner grading system in plain language. What ‘4AA’ actually means for your embryo.
PGT-A, PGT-M, PGT-SR — what each tests for. The honest data: per-transfer vs per-cycle live-birth rates. Mosaic embryos. India-specific legal frame (PNDT Act).
Why ‘freeze-all’ is becoming the modern default. The 2024 evidence on FET for PMOS / high responders. Natural vs hormone-replacement vs modified FET protocols.
What Endometrial Receptivity testing actually measures. When it's worth doing (recurrent failure, repeated euploid loss) and when it's selling false hope.
The structured work-up for ‘good embryos that didn't stick’. Hysteroscopy, thrombophilia panel, sperm DNA fragmentation. And the add-ons with weak evidence to skip.
Mini-IVF, batch-IVF, shared-risk programmes, corporate/insurance coverage. How to stretch the budget without compromising the chance.
When (and how) to take your case to another clinic. The file to carry. The 12 questions to ask the next doctor before signing up.
Donor egg / sperm IVF under the ART Act 2021. Embryo donation. Altruistic surrogacy (Surrogacy Regulation Act 2021). Fertility preservation / egg freezing.
Side-by-side comparison boxes for ‘which trigger’, ‘which transfer day’, ‘when ERA helps’, ‘when ICSI is needed’. The exact mental models Dr. Shafali uses in OPD.
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Yes if you're new to IVF. The IVF Basic Guide covers what IVF is, who it's for, success rates by age, and the 90-day pre-IVF prep. This advanced guide assumes you've already absorbed those basics and want the deeper protocol-level detail.
The patient. Specifically written so a couple can walk into their fertility clinic having understood the terms — and ask sharper questions about why their specific protocol was chosen.
Yes — most readers buy this mid-cycle. Chapters 4 (Day 3 vs Day 5), 5 (PGT) and 6 (fresh vs frozen) are written specifically for the in-cycle decision window.
No. It complements it. Your doctor knows your specific case; this guide helps you understand the framework your doctor is operating in, and the questions to ask if something doesn't add up.
Hindi and English, side-by-side.
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